Infertility

Infertility is one of the major health problems that affect a couple’s life. This happens when a couple cannot conceive a child in a year, despite the fact that they have unprotected sex regularly and do not use contraceptives. This health problem can be due to a man, a woman, or both.

 

 

Infertility in men

There is a wide range of infertility problems in men, from low sperm motility to very serious problems such as lack of sperm in the testicles.

Although there are many reasons that can cause infertility in men, the source of the problem can be determined to a very small extent. If no sperm are produced during ejaculation, sperm can be obtained by surgical methods. The IVF Center of Florence Nightingale Group works in collaboration with urologists for various diagnoses and treatment alternatives, as well as TESE-TESA-MESA methods, to obtain sperm.

IVF (in vitro fertilization)

IVF is the name of the whole process of collecting eggs from the candidate mother and sperm from the candidate father, fertilizing them in the laboratory and inserting the embryos into the mother’s uterus.

Florence Nightingale IVF Group offers state-of-the-art services with experienced staff and specialist clinicians. All micromanipulations, embryo freezing and thawing techniques, laser embryo manipulations, embryonic biopsies, preimplantation genetic diagnostic techniques, IMSI (morphologically selected intracytoplasmic sperm injection), embryoscope technique – primovision system, obtaining sperm by surgical methods and detailed endological investigations, are performed with high success rates.

IVF step by step – Ovule collection

On the day of ovule collection, under general anesthesia, under the conditions of an operating room, the ovules are collected through the vagina with ultrasonographic guidance. The development of embryos after fertilization by ICSI method (intracytoplasmic sperm microinjection) is monitored during their growth in laboratory conditions for 2-5 days.

IMSI (morphologically selected intracytoplasmic sperm injection)

The purpose of this technique is to select the highest quality sperm that would increase the rate of fertilization after microinjection. The best quality sperm and ovule affects the development of the embryo and increase the chances of the mother becoming pregnant.

In the usual procedure, a normal microscope with a magnification capacity of 400-600 times is used to select sperm to be used for the microinjection technique (ICSI – intracytoplasmic microinjection of sperm). In the IMSI technique, the sperm is selected by the microscopic system with a magnification capacity of 6000 times.

Embryoscope / PRIMO-VISION system

In the usual procedure, the embryo to be transferred is selected on examination before the transfer; nothing is known about the development of embryos until the time of examination.

There are some internal filming systems to see the embryos in the “Dynamic Embryo Monitoring System”. This video allows to see the development of embryos, from fertilization to selection. This is a period of about 5 days and is rendered as a sequential recording. When the necessary investigations are done, we have the opportunity to discover embryos that show better development.

Assisted hatching

The outer layer of the embryo (pellucid area) is opened mechanically or under a microscope, so the embryo is helped to hatch before being transferred to the uterus.

PGD ​​(preimplantation genetic diagnosis)

Despite choosing the best-shaped embryos, implantation (attachment to the uterus) and successful pregnancy are not 100%. Sometimes an embryo can be in very good shape, but it can be genetically abnormal.

The chance of these embryos forming a pregnancy is very low and even if the pregnancy occurs, the possibility of losing it is high.

Cases in which embryos may have the most common genetic disorders:

  1. If the woman is over 37 years old
  2. If the man has severe sperm abnormalities
  3. If the man or woman or a close relative has a chromosomal disorder / genetic disease or if they are carriers
  4. If IVF has been tried several times but the pregnancy has not developed
  5. In women who have had 3 or more miscarriages
  6. In couples with a birth history with a genetic disease

These embryos with genetic problems can be distinguished by PGD and only embryos with healthy chromosomes can be transferred.